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These days, psychedelic research is experiencing a renaissance of sorts. And Matt Johnson, a professor of psychiatry at Johns Hopkins, is leading the way. One of “the world’s most published scientists on the human effects of psychedelics,” his research focuses on “unraveling the scientific underpinnings of psychedelic substances, moving beyond their historical and cultural context to shed light on their role in modern therapeutic applications.” Like some other researchers before him, he believes that psychedelics ultimately have the “potential to bring about a paradigm shift in psychiatry, neuroscience, and pharmacology.” In the Big Think video above, the professor answers 24 big questions about psychedelics, from “What are the main effects of psychedelics?,” to “How do psychedelics work in the brain?” and “What are the biggest risks of psychedelics?,” to “Will psychedelics answer the hard problem of consciousness?” Johnson covers a lot of ground here. Settle in. The video runs 2+ hours.

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